Brian Knippelmeyer grew up in Lincoln, NE. He played at Lincoln Southeast High until 2002. He earned such honors as All City Team, All District Team, Cornhusker League All Star Team, and Nebraska Super State Honorable Mention as a 1B/RHP at Lincoln Southeast.
After high school he accepted a baseball scholarship at Barton Community College in Great Bend, KS. There he was a starting and middle relief pitcher. In two seasons with BCC he was 5-0 with a 3.56 ERA, 45 K's, 1 save, and a .204 opponent B/ Avg. After BCC he accepted a baseball scholarship with Marshall University in Huntington, WV. During his junior year he was their Sunday starter.
His senior year he was the closer on the pitching staff. During his time at Marshall he had the unique opportunity to play in two NCAA Division 1 conferences, the MAC and Conference USA. In two seasons with Marshall he was 3-8 with a 6.08 ERA, 88 K's (led team with 58 in 2005), and 5 saves which was 2nd all time for single season after 2006. During the 2006 season he earned conference honorable mention as a relief pitcher in Conference USA.
After he finished college baseball he returned to Marshall University in 2008 and served as a volunteer assistant working with pitchers and worked on their recruiting data base. From 2012 to 2014 he worked at Baseball Mentoring Program in Sacramento, CA as a pitching and hitting instructor. After moving to Kansas City in 2014 he became the manager for the NBA team in the Ban John Amateur League until 2016. In 2015, his team captured the Ban Johnson League Championship. In three Ban Johnson seasons, Knippelmeyer had a record of 57-40 (.587). From 2016 to 2017 Knippelmeyer was the pitching coach and top recruiter for the University of Saint Mary in Leavenworth, KS. In two seasons at USM, he helped Grant Arnold and Jeremy Melvin sign professional contracts in the Pecos League (Independent). In 2017, Knippelmeyer became an assistant coach for the Midwest A's in the Mid-Plains League.